Benefits of Korean Red Ginseng

Korean Red Ginseng

What is it?

Korean Red Ginseng, an herb that has been used for more than 5000 years in Asia, is one of the most widely researched herbs on the planet. Korean Red Ginseng's scientific name "Panax Ginseng" actually means "cure-all". It has been shown is scientific studies to increase energy, endurance, athletic performance, cognitive performance, mood, immune system, reduce stress response, and improve overall well being. Premium Essentials Korean Red Ginseng is a high potency root extract offering a 5% Ginsenoside content. Ginsenosides are the active component in Ginseng, and at a dosage of 500mg this supplement provides the perfect dosage.

Scientific Studies:

Fatigue and Endurance:

One study from Germany reported that trained athletes taking Korean Red Ginseng, also known as Panax Ginseng, experienced significant improvements in their aerobic capacity. A study from California State Polytechnic University reported that subjects taking Ginseng for 30 days increased their exercise time to exhaustion by more than seven minutes.

Another study in humans assessing Panax Ginseng ingestion at either 200mg or 400mg acutely in healthy young adults noted that 200mg was able to reduce a fall in mood associated with prolonged (4 hour) psychological testing and 400mg induced a state of calmness. There were no significantly different effects when comparing the first dose against the 8th consecutive daily dose, suggesting no tolerance nor build-up effect.

Another study replicated this reduction of fatigue with 200mg extract (4% Ginsenosides) where a 10 minute neural test was performed, followed by 50 minutes rest, and then the same test 6 times in immediate succession. 400mg was still effective, but less so than 200mg.

Cognition and Mood:

A study done at the Brain Performance and Nutrition Research Centre in the United Kingdom involving 30 volunteers found that 200 milligrams of ginseng for eight days slowed the fall in mood, but also slowed the participants' response to mental arithmetic. The 400 milligram dose improved calmness and improved mental arithmetic for the duration of the eight-day treatment.

A study in young healthy adults using 200 or 400mg acutely noted increased reaction time associated with 400mg, but not 200mg, 2.5 hours after ingestion. Interestingly, 200mg led to slightly but significantly slower reaction times on the first day of tested, which may have been secondary to an induction of calmess. These improvements in reaction time have been replicated with 400mg of 4% Ginsenoside extract in regards to spatial reaction time at the same time after ingestion.

Cerebrovascular Function:

A study done in humans assessing blood flow to the brain after Ginseng ingestion in healthy persons where 200mg G115 extract noted significantly reduced P300 latency (not amplitude) in all five tested cerebral lobes (main four, but left and right temporal tested independently) with significantly reduced beta and theta waveband power (in mV2/Hz) while alpha was reduced only in the frontal lobe, where beta and theta were more potent.

Erectile Disfunction:

In the treatment of erectile dysfunction (ED), one pilot study using 60 patients with mild to moderate ED were given 3g of Korean Red Ginseng in three daily doses of 1g with meals for 12 weeks. Korean Red Ginseng appeared to be effective, with 66.6% of the patients in the KRG group reported improved erections while the placebo group was not significantly different from baseline. Another blinded study with a larger sample (86) noted that regular Panax Ginseng over a period of 8 weeks, dosed at 1,000mg twice daily (daily dose totaling 2g) found significant improvements in erectile function as assessed by the same rating scale.

Immune Response:

Ginseng has been reported before as being a 'vaccine adjuvant', being able to amplify the efficacy of vaccines when Ginseng is in circulation when the vaccine is administered. It appears to have further synergy with aluminum hydroxide. Co-administration of ginseng extracts alongside the antigen appears to improve the immune antibody response. When administered in a 100mg dose to humans, it appears to have the ability to reduce the occurrence of the flu when the extract is taken for 12 weeks and the vaccination is applied at week 4. This human study noted that the addition of Ginseng brought the rate of flu occurrence down to 35.7% of the control group with no clinically relevant side effects recorded over 12 weeks.

Effects on Cancer:

Panax Ginseng is being investigated for its interactions with cancer due to observational (uncontrolled) evidence that usage of Panax Ginseng is associated with over 2-fold reduced risk of several types of cancer, with Odds Ratio (0.5 being half the risk, 0.25 a quarter the risk) being 0.47 for oropharyngeal cancers; 0.20 for esophageal cancer; 0.36 for stomach cancer; 0.42 for colorectal cancer; 0.48 for liver cancer; 0.22 for pancreatic cancer; 0.18 for laryngeal cancer; 0.55 for lung cancer; and 0.15 for ovarian cancer. Red Ginseng was associated with a greater risk reduction (0.2) than was fresh (0.37) or white (0.30-0.57)

Reduction of Wrinkles:

Oral ingestion of Red Ginseng has been shown to reduce wrinkles when consumed over 24 weeks by older women (average age of 51.9), although confounded with other supplements. Effects were seen at the first measurement of 12 weeks and held stable at 24 weeks, and this study failed to notice any significant differences when looking at skin pigmentation, water content of the skin, and the skin's elasticity and thickness.

Hearing and Ears:

Various tests with Korean Red Ginseng suggest that bioactives (most likely ginsenosides) in Ginseng can protect ear cells from toxicity induced by cisplatin and gentamicin, two compounds that have been shown to damage audition.

Combination with Ginkgo Biloba:

Ginkgo Biloba (found in Insight™) is another herb that has traditionally been used as a cognitive booster, and has been studied in conjunction with and alongside Panax Ginseng due to both of them being used traditionally for similar goals.

One study assessing 360mg Ginkgo against 400mg Panax ginseng as well as their combination against placebo found that the combination of the two was significantly more effective than either in isolation regarding simple reaction time (4 hours after ingestion), improving delayed word recall 1-4 hours after ingestion, and improving spatial memory.



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